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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFNB1
All Species:
5.45
Human Site:
S227
Identified Species:
13.33
UniProt:
P98172
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P98172
NP_004420.1
346
38007
S227
P
G
A
S
G
G
S
S
G
D
P
D
G
F
F
Chimpanzee
Pan troglodytes
XP_529024
368
39511
S243
P
G
A
S
G
G
S
S
G
D
P
D
G
F
F
Rhesus Macaque
Macaca mulatta
XP_001082851
738
79692
N627
G
D
P
D
G
F
F
N
S
K
V
A
L
F
A
Dog
Lupus familis
XP_849150
317
34681
D206
R
G
S
L
G
D
S
D
G
K
H
E
T
V
N
Cat
Felis silvestris
Mouse
Mus musculus
P52795
345
37841
G227
G
A
G
G
G
G
S
G
D
S
D
S
F
F
N
Rat
Rattus norvegicus
P52796
345
37933
G227
G
A
G
G
S
G
S
G
D
T
D
S
F
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512874
312
34324
S202
S
G
N
N
I
L
G
S
E
V
A
L
F
A
G
Chicken
Gallus gallus
O73612
334
36840
L223
Q
G
P
S
D
G
F
L
S
S
K
V
A
V
F
Frog
Xenopus laevis
O13097
329
36574
F218
G
G
G
V
D
G
F
F
N
S
K
I
A
V
F
Zebra Danio
Brachydanio rerio
O73874
332
36706
V221
S
S
V
I
G
S
E
V
A
L
F
A
C
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.5
44.3
87.8
N.A.
95.6
94.8
N.A.
51.4
77.4
72.5
52.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.3
44.5
88.7
N.A.
96.8
96.5
N.A.
67
87.8
85.2
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
26.6
N.A.
26.6
20
N.A.
13.3
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
40
N.A.
26.6
20
N.A.
20
26.6
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
20
0
0
0
0
0
10
0
10
20
20
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
10
20
10
0
10
20
20
20
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
30
10
0
0
10
0
30
50
40
% F
% Gly:
40
60
30
20
60
60
10
20
30
0
0
0
20
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
20
20
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
0
10
0
10
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
10
10
0
0
0
0
0
30
% N
% Pro:
20
0
20
0
0
0
0
0
0
0
20
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
10
10
30
10
10
50
30
20
30
0
20
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
10
10
0
0
0
10
0
10
10
10
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _